diff --git a/readme.md b/readme.md index c291be9..fa8e894 100644 --- a/readme.md +++ b/readme.md @@ -12,7 +12,7 @@ Unlike pairSEQ, which calculates p-values for every TCR alpha/beta overlap and c against a null distribution, BiGpairSEQ does not do any statistical calculations directly. -BiGpairSEQ creates a [weightd bipartite graph](https://en.wikipedia.org/wiki/Bipartite_graph) representing the sample plate. +BiGpairSEQ creates a [weighted bipartite graph](https://en.wikipedia.org/wiki/Bipartite_graph) representing the sample plate. The distinct TCRA and TCRB sequences form the two sets of vertices. Every TCRA/TCRB pair that share a well are connected by an edge, with the edge weight set to the number of wells in which both sequences appear. (Sequences present in *all* wells are filtered out prior to creating the graph, as there is no signal in their occupancy pattern.)