Compare commits
2 Commits
ab8d98ed81
...
dad0fd35fd
| Author | SHA1 | Date | |
|---|---|---|---|
| dad0fd35fd | |||
| 35d580cfcf |
11
readme.md
11
readme.md
@@ -131,10 +131,13 @@ Options when making a Sample Plate file:
|
|||||||
* Standard deviation size
|
* Standard deviation size
|
||||||
* Exponential
|
* Exponential
|
||||||
* Lambda value
|
* Lambda value
|
||||||
* *(Based on the slope of the graph in Figure 4C of the pairSEQ paper, the distribution of the original experiment was exponential with a lambda of approximately 0.6. (Howie, et al. 2015))*
|
* *(Based on the slope of the graph in Figure 4C of the pairSEQ paper, the distribution of the original experiment was approximately exponential with a lambda ~0.6. (Howie, et al. 2015))*
|
||||||
* Total number of wells on the plate
|
* Total number of wells on the plate
|
||||||
* Number of sections on plate
|
* Well populations random or fixed
|
||||||
* Number of T cells per well
|
* If random, minimum and maximum population sizes
|
||||||
|
* If fixed
|
||||||
|
* Number of sections on plate
|
||||||
|
* Number of T cells per well
|
||||||
* per section, if more than one section
|
* per section, if more than one section
|
||||||
* Dropout rate
|
* Dropout rate
|
||||||
|
|
||||||
@@ -260,7 +263,7 @@ slightly less time than the simulation itself. Real elapsed time from start to f
|
|||||||
* ~~Apache Commons CSV library writes entries a row at a time~~
|
* ~~Apache Commons CSV library writes entries a row at a time~~
|
||||||
* _Got this working, but at the cost of a profoundly strange bug in graph occupancy filtering. Have reverted the repo until I can figure out what caused that. Given how easily Thingiverse transposes CSV matrices in R, might not even be worth fixing._
|
* _Got this working, but at the cost of a profoundly strange bug in graph occupancy filtering. Have reverted the repo until I can figure out what caused that. Given how easily Thingiverse transposes CSV matrices in R, might not even be worth fixing._
|
||||||
* Re-implement command line arguments, to enable scripting and statistical simulation studies
|
* Re-implement command line arguments, to enable scripting and statistical simulation studies
|
||||||
* Implement sample plates with random numbers of T cells per well.
|
* ~~Implement sample plates with random numbers of T cells per well.~~ DONE
|
||||||
* Possible BiGpairSEQ advantage over pairSEQ: BiGpairSEQ is resilient to variations in well population sizes on a sample plate; pairSEQ is not.
|
* Possible BiGpairSEQ advantage over pairSEQ: BiGpairSEQ is resilient to variations in well population sizes on a sample plate; pairSEQ is not.
|
||||||
* preliminary data suggests that BiGpairSEQ behaves roughly as though the whole plate had whatever the *average* well concentration is, but that's still speculative.
|
* preliminary data suggests that BiGpairSEQ behaves roughly as though the whole plate had whatever the *average* well concentration is, but that's still speculative.
|
||||||
* Enable GraphML output in addition to serialized object binaries, for data portability
|
* Enable GraphML output in addition to serialized object binaries, for data portability
|
||||||
|
|||||||
Reference in New Issue
Block a user