4 Commits

Author SHA1 Message Date
b4cc240048 Update Readme 2022-02-26 11:03:31 -06:00
ff72c9b359 Update Readme 2022-02-26 11:02:23 -06:00
88eb8aca50 Update Readme 2022-02-26 11:01:44 -06:00
98bf452891 Update Readme 2022-02-26 11:01:20 -06:00

View File

@@ -105,6 +105,7 @@ The program's caching behavior can be controlled in the Options menu. By default
The program can optionally output Graph/Data files in .GraphML format (.graphml) for data portability. This can be The program can optionally output Graph/Data files in .GraphML format (.graphml) for data portability. This can be
turned on in the Options menu. By default, GraphML output is OFF. turned on in the Options menu. By default, GraphML output is OFF.
---
#### Cell Sample Files #### Cell Sample Files
Cell Sample files consist of any number of distinct "T cells." Every cell contains Cell Sample files consist of any number of distinct "T cells." Every cell contains
four sequences: Alpha CDR3, Beta CDR3, Alpha CDR1, Beta CDR1. The sequences are represented by four sequences: Alpha CDR3, Beta CDR3, Alpha CDR1, Beta CDR1. The sequences are represented by
@@ -122,7 +123,6 @@ Comments are preceded by `#`
Structure: Structure:
---
# Sample contains 1 unique CDR1 for every 4 unique CDR3s. # Sample contains 1 unique CDR1 for every 4 unique CDR3s.
| Alpha CDR3 | Beta CDR3 | Alpha CDR1 | Beta CDR1 | | Alpha CDR3 | Beta CDR3 | Alpha CDR1 | Beta CDR1 |
|---|---|---|---| |---|---|---|---|
@@ -167,7 +167,6 @@ Dropout sequences are replaced with the value `-1`. Comments are preceded by `#`
Structure: Structure:
---
``` ```
# Cell source file name: # Cell source file name:
# Each row represents one well on the plate # Each row represents one well on the plate
@@ -223,7 +222,6 @@ Options when running a BiGpairSEQ simulation of CDR3 alpha/beta matching:
Example output: Example output:
---
``` ```
# Source Sample Plate file: 4MilCellsPlate.csv # Source Sample Plate file: 4MilCellsPlate.csv
# Source Graph and Data file: 4MilCellsPlateGraph.ser # Source Graph and Data file: 4MilCellsPlateGraph.ser
@@ -290,7 +288,7 @@ slightly less time than the simulation itself. Real elapsed time from start to f
* ~~Apache Commons CSV library writes entries a row at a time~~ * ~~Apache Commons CSV library writes entries a row at a time~~
* _Got this working, but at the cost of a profoundly strange bug in graph occupancy filtering. Have reverted the repo until I can figure out what caused that. Given how easily Thingiverse transposes CSV matrices in R, might not even be worth fixing. * _Got this working, but at the cost of a profoundly strange bug in graph occupancy filtering. Have reverted the repo until I can figure out what caused that. Given how easily Thingiverse transposes CSV matrices in R, might not even be worth fixing.
* ~~Enable GraphML output in addition to serialized object binaries, for data portability~~ DONE * ~~Enable GraphML output in addition to serialized object binaries, for data portability~~ DONE
* ~~Custom vertex type with attribute for sequence occupancy?~~ABANDONED * ~~Custom vertex type with attribute for sequence occupancy?~~ ABANDONED
* Have a branch where this is implemented, but there's a bug that broke matching. Don't currently have time to fix. * Have a branch where this is implemented, but there's a bug that broke matching. Don't currently have time to fix.
* Re-implement command line arguments, to enable scripting and statistical simulation studies * Re-implement command line arguments, to enable scripting and statistical simulation studies
* Re-implement CDR1 matching method * Re-implement CDR1 matching method